Actions of Vitamin D and Its Metabolites

Organ

Actions

Bone

Promotes bone formation by maintaining appropriate calcium and phosphate concentrations

Immune system

Stimulates immunogenic and antitumor activity

Decreases risk of autoimmune disorders

Intestine

Enhances calcium and phosphate transport (absorption)

Kidneys

Enhances calcium reabsorption by the tubules

Parathyroid glands

Inhibits parathyroid hormone secretion

Pancreas

Stimulates insulin production