Possible Effects of Drugs on Mineral Metabolism

Drugs

Effects

Diuretics, especially thiazides, and corticosteroids

Can deplete body potassium*

Laxatives if used repeatedly

May deplete potassium*

Cortisol, desoxycorticosterone, and aldosterone

Cause marked sodium and water retention, at least temporarily

Impair uptake or release of iodine by the thyroid

Oral contraceptives

Certain antibiotics (eg, tetracyclines)

Reduce iron absorption