Cholesterol Levels and Cardiovascular Risk
Cardiovascular Risk | Total Cholesterol | LDL-C | HDL-C |
|---|---|---|---|
Higher risk | ≥ 6.2 mmol/L (240 mg/dL) | ≥ 4.1 mmol/L (160 mg/dL) | Male: < 1.0 mmol/L (40 mg/dL) Female: < 1.3 mmol/L (50 mg/dL) |
At- risk | 5.2-6.2 mmol/L (200-239 mg/dL) | 2.6-4.1 mmol/L (100-159 mg/dL) | Male: 1.0-1.5 mmol/L (40-59 mg/dL) Female: 1.3-1.5 mmol/L (50-59 mg/dL) |
Lower risk | < 5.2 mmol/L (200 mg/dL) | < 2.6 mmol/L (100 mg/dL) | ≥ 1.6 mmol/L (60 mg/dL )* |
* Evidence supports a U-shaped curve between HDL levels and cardiac risk, with possible increased risk associated with very elevated HDL. (Mørland JG, Magnus P, Vollset SE, Leon DA, Selmer R, Tverdal A. Associations between serum high-density lipoprotein cholesterol levels and cause-specific mortality in a general population of 345 000 men and women aged 20-79 years. Int J Epidemiol 2023;52(4):1257-1267. doi:10.1093/ije/dyad011) | |||
HDL = high-density lipoprotein; LDL = low-density lipoprotein. | |||
Data from Carmena R: Primary Mixed Dyslipidemias, Editor(s): Ilpo Huhtaniemi, Luciano Martini, Encyclopedia of Endocrine Diseases (Second Edition), Academic Press, 2019, Pages 314-319, ISBN 9780128122006, https://doi.org/10.1016/B978-0-12-801238-3.65333-3. | |||