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How Is Community-Acquired Pneumonia Treated?

Severity

Possible Medications

Comments

Mild pneumonia in otherwise healthy people with no risk factors*

AmoxicillinAmoxicillin

AzithromycinAzithromycin

ClarithromycinClarithromycin

DoxycyclineDoxycycline

Medications are taken by mouth.

People are treated at home.

Mild pneumonia in people with risk factors*

AmoxicillinAmoxicillin

Amoxicillin/clavulanateAmoxicillin/clavulanate

AzithromycinAzithromycin

CefpodoximeCefpodoxime

CefuroximeCefuroxime

ClarithromycinClarithromycin

DoxycyclineDoxycycline

LevofloxacinLevofloxacin

MoxifloxacinMoxifloxacin

Medications are usually taken by mouth.

Often, more than one medication is taken.

People are treated at home.

Moderate pneumonia

or

Pneumonia in people who cannot care for themselves

AzithromycinAzithromycin

CefotaximeCefotaxime

CeftriaxoneCeftriaxone

LevofloxacinLevofloxacin

MoxifloxacinMoxifloxacin

Medications are usually given intravenously in a hospital.

Often, more than one medication is given.

Severe pneumonia in people with many risk factors*

Some of the same medications used for moderate pneumonia

AztreonamAztreonam

CefepimeCefepime

CiprofloxacinCiprofloxacin

Imipenem/cilastatinImipenem/cilastatin

MeropenemMeropenem

Piperacillin/tazobactam

Medications are usually given intravenously in an intensive care unit.

Usually, more than one medication is given.

* Risk factors include heart or lung disorders, cancer, alcohol use disorder, age older than 65 years, recent use of antibiotics, and a weakened immune system (for example, because of HIV, organ transplantation, or use of medications that suppress the immune system).