Age >60 years old (1 point)
		Serum lactate dehydrogenase concentartion above normal (1 point)
		Ann Arbor stage III or IV (1 point)
		More than one extranodal disease site (1 point)
ECOG performance scale
		Performance status 0: Fully active; no performance restrictions (0 points)
		Performance status 1: Strenuous physical activity restricted; fully ambulatory and able to carry out light work (0 points)
		Performance status 2: Capable of all self-care but unable to carry out any work activities. Up and about >50 percent of waking hours (1 point)
		Performance status 3: Capable of only limited self-care; confined to bed or chair >50 percent of waking hours (1 point)
		Performance status 4: Completely disabled; cannot carry out any self-care; totally confined to bed or chair (1 point)

Total Criteria Point Count:
 

 

0 to 1 point:	Low risk with 73% 5 year OS and 87% CR
2 points:	Low-intermediate risk with 51% 5 year OS and 67% CR
3 points:	High-intermediate risk with 43% 5 year OS and 55% CR
4 to 5 points:	High risk with 26% 5 year OS and 44% CR

 

 

0 to 1 point:	EFS 81%, PFS 87% and OS 91%
2 points:	EFS 69%, PFS 75% and OS 81%
3 points:	EFS 53%, PFS 59% and OS 65%
4 to 5 points:	EFS 50%, PFS 50% and OS 59%