Rheumatoid Arthritis Clinical Disease Activity Index CDAI

 
Input
 
PGA  
EGA  

 
Tender Joint Count
   Shoulder
   Elbow
   Wrist

 Right hand
  MCP 1-5
IP 1, PIP 2-5








   
 
 
 








  Knee
Shoulder  
Elbow  
Wrist  
Left hand
MCP 1-5
IP 1, PIP 2-5		  








 
 
 
 










Knee  
TJC          
    
Swollen Joint Count
   Shoulder
   Elbow
   Wrist

 Right hand
  MCP 1-5
IP 1, PIP 2-5








   
 
 
 








  Knee
Shoulder  
Elbow  
Wrist  
Left hand
MCP 1-5
IP 1, PIP 2-5		  








 
 
 
 










Knee  
SJC          

 
Result
 
 
CDAI  
 
Decimal Precision  

 

 CDAI Interpretation

 
CDAI <= 2.8: Remission
CDAI > 2.8 and <= 10: Low Disease Activity
CDAI > 10 and <= 22: Moderate Disease Activity
CDAI > 22: High Disease Activity

 
 

 
Notes
  • In the hands, the joints that are evaluated include the first through fifth metacarpophalangeal joint, the interphalangeal joint of the thumb, and the second through fifth proximal interphalangeal joint.
  • The PGA or Patient Global disease Activity estimate represents the patient's self assessment of disease activity on a 0-10 scale where 10 means maximal activity.
  • The EGA or Evaluator Global disease Activity estimate represents the evaluator's assessment of disease activity on a 0-10 scale where 10 means maximal activity.
  • A CDAI reduction by 6.5 represents a moderate improvement.

 
Equations used
 
CDAI = SJC + TJC + PGA + EGA

 

 
References
  1. Aletaha D, Nell VP, Stamm T, et al. Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score. Arthritis Res Ther. 2005;7(4):R796-806. PubMed ID: 15987481 PubMed Logo
  2. Aletaha D, Smolen J. The Simplified Disease Activity Index (SDAI) and the Clinical Disease Activity Index (CDAI): a review of their usefulness and validity in rheumatoid arthritis. Clin Exp Rheumatol. 2005 Sep-Oct;23(5 Suppl 39):S100-8. PubMed ID: 16273793 PubMed Logo

 

 
 

 
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