Causes of Glomerulonephritis

Type

Examples

Primary

Idiopathic

Fibrillary and immunotactoid GN

Idiopathic crescentic GN

IgA nephropathy

Membranoproliferative GN

Secondary

Bacterial*

Group A beta-streptococcal infection

Mycoplasma infection

Neisseria meningitidis infection

Salmonella typhi infection

Staphylococcal infections (especially bacterial endocarditis)

Streptococcus pneumoniae infection

Visceral abscesses (due to Escherichia coli or Pseudomonas, Proteus, Klebsiella, or Clostridium species)

Parasitic*

Malaria (due to Plasmodium falciparum or P. malariae)

Schistosomiasis (due to Schistosoma mansoni)

Viral*

Coxsackievirus infection

Cytomegalovirus infection

Epstein-Barr virus infection

Hepatitis B

Hepatitis C

Herpes zoster

Measles

Mumps

Varicella

Other infectious and postinfectious causes

Fungal infections (due to Candida albicans [candidiasis] or Coccidioides immitis [coccidiomycosis])

Rickettsial infection

Systemic rheumatic diseases

Eosinophilic granulomatosis with polyangiitis

Granulomatosis with polyangiitis

IgA–associated vasculitis

Microscopic polyangiitis

Polyarteritis nodosa

SLE

Drug-induced disorders

SLE

Hemolytic-uremic syndrome

Hematologic dyscrasias

Mixed IgG-IgM cryoglobulinemia

Serum sickness

Thrombotic thrombocytopenic purpura–hemolytic-uremic syndrome

Glomerular basement membrane diseases

Goodpasture syndrome

Hereditary disorders

Alport syndrome

Thin basement membrane disease

* Infectious and postinfectious causes.

GN = glomerulonephritis; IgA = immunoglobulin A; IgM = immunoglobulin M;SLE = systemic lupus erythematosus.