Oral Calcium Channel Blockers for Hypertension

Nondihydropyridines

Headache, dizziness, asthenia, flushing, peripheral edema, bradycardia; possibly liver dysfunction

Possible gingival hyperplasia with chronic use

Contraindicated in heart failure with reduced ejection fraction due to negative inotropic effects, in sinus node dysfunction, or in greater than 1st-degree atrioventricular block

Headache, dizziness, asthenia, flushing, peripheral edema, bradycardia; possibly liver dysfunction

Constipation

Possible gingival hyperplasia with chronic use

Contraindicated in heart failure with reduced ejection fraction due to negative inotropic effects, in sinus node dysfunction, or in greater than 1st-degree atrioventricular block

Dihydropyridines

Dizziness, flushing, headache, weakness, nausea, heartburn, peripheral edema, tachycardia

Possible gingival hyperplasia with chronic use