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ENGLISH
MERCK MANUAL
Consumer Version
HEALTH TOPICS
HEALTHY LIVING
SYMPTOMS
EMERGENCIES
DRUG INFO
RESOURCES
COMMENTARY
ABOUT US
HEALTH TOPICS
HEALTHY LIVING
SYMPTOMS
EMERGENCIES
DRUG INFO
RESOURCES
COMMENTARY
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Drugs
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Overview of Drugs
Overview of Drugs
Prescription drugs or nonprescription drugs
Drug names
Drug groups
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Drug Design and Development
Stages of Drug Development
Early development
Clinical studies
Approval
Phase 4 (postmarketing)
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Placebos
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Drug Effectiveness and Safety
Making the Most of Drug Treatment
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Drug Errors
Using medication organizers
Understanding prescriptions
Prescribing drugs
Dispensing and administering drugs
Storing drugs properly
Taking expired drugs
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Administration and Kinetics of Drugs
Introduction to Administration and Kinetics of Drugs
Drug Administration
Oral route
Injection routes
Sublingual and buccal routes
Rectal route
Vaginal route
Ocular route
Otic route
Nasal route
Inhalation route
Nebulization route
Cutaneous route
Transdermal route
Drug Absorption
Tablets
Capsules
Enteric coatings
Controlled-release formulations
Causes of Low Bioavailability
Drug Distribution Within the Body
Drug Metabolism
Drug Elimination
Drug elimination in the urine
Drug elimination in the bile
Other forms of drug elimination
Nanomedicine
Adverse Drug Reactions
Overview of Adverse Drug Reactions
Prevalence of adverse drug reactions
Common adverse drug reactions
Identification and reporting of adverse drug reactions
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Types of Adverse Drug Reactions
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Severity of Adverse Drug Reactions
Mild adverse drug reactions
Moderate adverse drug reactions
Severe adverse drug reactions
Lethal adverse drug reactions
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Benefits Versus Risks of Drugs
Risk Factors for Adverse Drug Reactions
Use of Several Drugs
Age
Pregnancy and Breastfeeding/Chestfeeding
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Allergies to Drugs
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Overdose Toxicity
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Brand-Name and Generic Drugs
Overview of Generic Drugs and Drug Naming
Patent Protection for Drugs
Nonprescription Generic Drugs
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Bioequivalence and Interchangeability of Generic Drugs
Bioequivalence
Evaluation and approval procedures
Interchangeability and substitution
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Generic Biologic Drugs
Drug Dynamics
Definition of Drug Dynamics
Drug Action
Reversibility
Affinity and Intrinsic Activity
Potency, Efficacy, and Effectiveness
Site Selectivity
Receptors on Cells
Agonists and antagonists
Enzymes
Chemical Interactions
Factors Affecting Response to Medications
Overview of Response to Medications
Effects of age on drug response
Adherence to Medication
Results of not adhering
Children and adherence
Older adults and adherence
Improving adherence
Drug Interactions
Drug-Drug Interactions
Duplication
Opposition (antagonism)
Alteration
Drug-Nutrient Interactions
Food
Dietary supplements
Alcohol
Drug-Disease Interactions
Genetic Makeup and Response to Medications
Tolerance and Resistance to Medications
Tolerance
Resistance
Prevention and Treatment
Over-the-Counter Medications
Overview of Over-the-Counter Medications
History of Medication Regulation in the United States
Safety Considerations
Reclassifying prescription medications as over-the-counter medications
Choosing and using over-the-counter medications
Reading the labels of over-the-counter medications
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Precautions With Over-the-Counter Medications
Children
Older Adults
Pregnant and Breastfeeding Women
People With Chronic Disorders
Drug-Drug Interactions
Medication Overlap
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