Postprandial Hypotension

ByAndrea D. Thompson, MD, PhD, University of Michigan;
Michael J. Shea, MD, Michigan Medicine at the University of Michigan
Reviewed/Revised Aug 2024
VIEW PROFESSIONAL VERSION

Postprandial hypotension is an excessive decrease in blood pressure that occurs after a meal.

  • Dizziness, light-headedness, and falls may occur.

  • Doctors measure blood pressure before and after a meal to diagnose postprandial hypertension.

  • Eating small, low-carbohydrate meals frequently may help.

Postprandial hypotension occurs in up to one-third of older adults but virtually never occurs in younger people. It is more likely to occur in people who have high blood pressure or disorders that impair the brain centers controlling the autonomic nervous system (which regulates internal body processes). Examples of such disorders are Parkinson disease, multiple system atrophy, and diabetes.

The intestine requires a large amount of blood for digestion. When blood flows to the intestine after a meal, the heart rate increases and blood vessels in other parts of the body constrict to help maintain blood pressure. However, in some older adults, such mechanisms may be inadequate. Blood flows normally to the intestine, but the heart rate does not increase adequately and blood vessels do not constrict enough to maintain blood pressure. As a result, blood pressure falls.

Postprandial hypotension can cause dizziness, light-headedness, faintness, and falls. If an older adult experiences these symptoms after eating, doctors measure blood pressure before and after meals to determine if postprandial hypotension is the cause.

Treatment of Postprandial Hypotension

  • Adjust medication timing and activities around meals

People who have symptoms of postprandial hypotension should not take antihypertensive medications before meals and should lie down after meals. Taking a smaller dose of the antihypertensive medications, eating small, low-carbohydrate meals more frequently, and drinking more fluids may help reduce the effects of this disorder. For some people, walking after a meal helps improve blood flow, but blood pressure may fall when they stop walking.

Taking certain medications before a meal may help. For example, nonsteroidal anti-inflammatory drugs (NSAIDs) cause salt to be retained and thus increase blood volume. Caffeine causes blood vessels to constrict. Caffeine should usually be taken only before breakfast so that sleep is not affected and the person does not become tolerant of caffeine's effects.

Drugs Mentioned In This Article
quizzes_lightbulb_red
Test your KnowledgeTake a Quiz!
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID