Glycopeptides and Lipoglycopeptides

ByBrian J. Werth, PharmD, University of Washington School of Pharmacy
Reviewed/Revised May 2024
VIEW PROFESSIONAL VERSION

Glycopeptides and lipoglycopeptides are antibiotics used to treat complicated and/or serious infections caused by gram-positive bacteria.

Glycopeptides and lipoglycopeptides include the following:

  • Dalbavancin

  • Oritavancin

  • Teicoplanin

  • Telavancin

  • Vancomycin

Most bacteria have an outer covering (cell wall) that protects them. Glycopeptides and lipoglycopeptides work by preventing gram-positive bacteria from forming this cell wall, resulting in the death of the bacteria.

Table

(See also Overview of Antibiotics.)

Use of Glycopeptides and Lipoglycopeptides During Pregnancy and Breastfeeding

Use of glycopeptides and lipoglycopeptides during pregnancy is not recommended, but sometimes the benefits of treatment may outweigh the risks. For example, vancomycin taken by mouth may be used to treatC. difficile–induced diarrhea in pregnant women. (See also Safety of Medications During Pregnancy.)

Use of glycopeptides and lipoglycopeptides during breastfeeding is discouraged. (See also Medication and Substance Use During Breastfeeding.)

Drugs Mentioned In This Article

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