Byssinosis

ByCarrie A. Redlich, MD, MPH, Yale Occupational and Environmental Medicine Program Yale School of Medicine;
Efia S. James, MD, MPH, Bergen New Bridge Medical Center;Brian Linde, MD, MPH, Yale Occ and Env Medicine Program
Reviewed/Revised Nov 2023
VIEW PROFESSIONAL VERSION

Byssinosis is a narrowing of the airways (asthma-like syndrome) caused by inhaling cotton, flax, or hemp particles.

  • Byssinosis may cause shortness of breath, wheezing, and tightness in the chest, usually on the first day of work after a break.

  • The diagnosis is made by using a test that shows decreasing lung function over the course of a workday.

  • Exposure should be stopped, then wheezing and chest tightness can be treated with medications used for asthma.

(See also Overview of Environmental and Occupational Lung Disease.)

Causes of Byssinosis

Byssinosis is an asthma-like syndrome that occurs in textile workers who come into contact with unprocessed, raw cotton, flax, or hemp. Specific textile mill jobs are associated with a higher risk of byssinosis.

Evidence suggests that inhaling a substance in cotton dust leads to narrowing of the airways, chronic bronchitis, and a gradual decrease in lung function. Experts believe a toxin produced by bacteria in raw cotton becomes mixed with cotton dust and causes the airways of susceptible people to narrow.

Symptoms of Byssinosis

Symptoms include chest tightness and shortness of breath that lessen with repeated exposure. Symptoms develop on the first day of work after a weekend or vacation and diminish or disappear with subsequent continuous workdays. This typical time pattern distinguishes byssinosis from asthma.

Textile workers with chronic (5 to 10 years or more) exposure to cotton or other dusts can develop obstructive lung disease that has features of both asthma and chronic obstructive pulmonary disease (COPD).

Diagnosis of Byssinosis

  • History of exposure and results of lung function tests

Doctors base the diagnosis of byssinosis on the person's history of exposure to cotton, flax, or hemp dust and on lung function tests that show airflow obstruction.

Doctors recommend that people who work in the textile industry undergo regular pulmonary function testing in order to detect byssinosis early.

Treatment of Byssinosis

  • Medications to open airways

Treatment of byssinosis includes avoidance or reduction of exposure and use of medications that treat COPD and asthma.

Dust exposure can be reduced by wetting procedures, increases in general ventilation, and the use of exhaust hoods. For some tasks, respiratory protection may be required. Workers with persistent symptoms or in whom pulmonary function tests indicate significant obstruction should move to areas of lower exposure.

Prevention of Byssinosis

Controlling dust and using protective devices, such as respirators, dust masks, and other equipment, are the best ways to prevent byssinosis.

quizzes_lightbulb_red
Test your KnowledgeTake a Quiz!
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID