Discrimination based on race or sexual orientation or gender identity
Being the victim of bullying (for example, cyberbullying, social rejection, discrimination, humiliation, disgrace)
Work disruption (for example, unemployment) and periods of transition (for example, going from active duty to veteran status, retiring)
Financial stress from economic downturns, debt, or underemployment
Bereavement or loss (eg, death of family or friends)
Relationship conflict (eg, divorce)
Legal problems
Social isolation
Depression (especially when accompanied by anxiety, as part of major depression or bipolar disorder, or associated with recent hospitalization), personality disorders, anorexia or bulemia (in women), schizophrenia, anxiety disorders
Medical illness, particularly one that is painful or disabling or affects the brain
Aggressive, impulsive, or hostile behavior
Feelings of sadness, guilt, or hopelessness (when persistent)
Substance or alcohol use disordersincluding alcohol, opioids, and other prescription and nonprescription drugs and medications
