Peliosis Hepatis

ByWhitney Jackson, MD, University of Colorado School of Medicine
Reviewed/Revised May 2024
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    Peliosis hepatis is typically an asymptomatic disorder in which multiple blood-filled cystic spaces develop randomly in the liver.

    (See also Overview of Vascular Disorders of the Liver.)

    Peliosis hepatis is usually asymptomatic, but occasionally cysts rupture, resulting in hemorrhage and sometimes causing death. Some patients develop overt liver disease, characterized by jaundice, hepatomegaly, and liver failure.

    Mild cases may be detected incidentally during imaging tests done because liver test results are slightly abnormal or for other reasons. Ultrasonography or CT can detect cysts.

    Most cases are not treated.

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