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Surgical Procedure	Approved Antibiotics
Cardiac or vascular	Cefazolin, cefuroxime, or vancomycin If beta-lactam allergy: Vancomycin or clindamycin
Hip/knee arthroplasty	Cefazolin, cefuroxime, or vancomycin If beta-lactam allergy: Vancomycin or clindamycin
Colon	Cefotetan, cefoxitin, ampicillin/sulbactam, or ertapenemorcefazolin plus metronidazoleorcefuroxime plus metronidazoleorceftriaxone plus metronidazole If beta-lactam allergy: Clindamycin plus gentamicinorclindamycin plus ciprofloxacinorclindamycin plus aztreonamormetronidazole plus gentamicinormetronidazole plus ciprofloxacin
Hysterectomy	Cefotetan, cefazolin, cefoxitin, cefuroxime, or ampicillin/sulbactam If beta-lactam allergy: Clindamycin plus gentamicinorclindamycin plus ciprofloxacinorclindamycin plus aztreonamormetronidazole plus gentamicinormetronidazole plus ciprofloxacinorvancomycin plus aminoglycosideorvancomycin plus aztreonamorvancomycin plus quinolone
Adapted from the Specifications Manual for Joint Commission National Quality Core Measures.