Antibiotic Regimens for Treatment of Intraamniotic Infection

Recommended Antibiotics

  1. and

Recommended Antibiotics (Mild Penicillin Allergy)

  1. and

Recommended Antibiotics (Severe Penicillin Allergy)

  1. or

  2. and

Postcesarean delivery:

Postvaginal delivery:

Alternative Regimens

  1. Piperacillin-tazobactam 3.375 g IV every 6 hours or 4.5 g IV every 8 hours

Postcesarean delivery:

Postvaginal delivery:

American College of Obstetricians and Gynecologists: Committee Opinion No. 712: Intrapartum Management of Intraamniotic Infection. Obstet Gynecol. 2017 (reaffirmed 2022); 130(2):e95-e101. doi:10.1097/AOG.0000000000002236