Comparison of Hodgkin Lymphoma and Non-Hodgkin Lymphoma

Feature

Hodgkin Lymphoma

Non-Hodgkin Lymphoma

Nodal involvement

Typically localized to a specific group of nodes

Usually disseminated among > 1 nodal group

Spread

Tends to spread in an orderly, contiguous fashion

Spreads noncontiguously

Effect on Waldeyer ring and mesenteric lymph nodes

Usually does not affect

Commonly affects mesenteric nodes

May affect Waldeyer ring

Extranodal involvement

Infrequent

Frequent

Stage at diagnosis

Often early

Usually advanced

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