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Differentiation of Generalized Hypopituitarism from Other Selected Disorders

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Disorder	Differentiating Features
Anorexia nervosa	Female predominance; cachexia; abnormal ideation regarding food and body image; maintenance of secondary sexual characteristics despite amenorrhea; increased levels of basal growth hormone and cortisol
Alcohol-related liver disease or hemochromatosis*	Evidence of liver disease; laboratory testing
Myotonia dystrophica	Progressive weakness; premature balding; cataracts; facial features of accelerated aging; laboratory testing
Polyglandular autoimmune disease†	Pituitary hormone levels
* May cause hypogonadism and general debility.
† If the affected glands are target glands of the pituitary.