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Grading of Mitral Regurgitation

Parameter

Moderate MR

Severe MR

Vena contracta*

3–7 mm

> 7 mm

Effective regurgitant orifice area

0.20–0.40 cm2

> 0.40 cm2

Regurgitant volume

30–60 mL

> 60 mL

Regurgitant fraction

30–50%

> 50%

* The narrowest diameter of the fluid stream downstream of an abnormal valve orifice; it is slightly smaller than the anatomic valve orifice.

MR = mitral regurgitation.

Data from Otto CM, Nishimura RA, Bonow RO, et al: 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 143(5):e35–e71, 2021. doi: 10.1161/CIR.0000000000000932

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