Lipoprotein Patterns (Fredrickson Phenotypes)
Phenotype | Elevated Lipoprotein(s) | Elevated Lipids |
|---|---|---|
I | Chylomicrons | TGs |
IIa* | LDL | Cholesterol |
IIb* | LDL and VLDL | TGs and cholesterol |
III | VLDL and chylomicron remnants | TGs and cholesterol |
IV | VLDL | TGs |
V | Chylomicrons and VLDL | TGs and cholesterol |
* The names of some primary disorders reflect an old nomenclature in which lipoproteins were detected and distinguished by how they separated into alpha (HDL) and beta (LDL) bands on electrophoretic gels. | ||
LDL = low-density lipoprotein; TGs = triglycerides; VLDL = very-low-density lipoprotein. | ||
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