Location of Thrills and Associated Disorder

Over the base of the heart at the 2nd intercostal space, just to the right of the sternum, during systole

Aortic stenosis

At the apex during systole

Mitral regurgitation

To the left of the sternum at the 2nd intercostal space

Pulmonic stenosis

To the left of the sternum at the 4th intercostal space

Small muscular ventricular septal defect (Roger disease)