Preferred Breast Cancer Adjuvant Systemic Therapy*
Axillary Lymph Node | ER+ and/or PR+ | ER− and PR− |
|---|---|---|
Premenopausal | ||
Negative† | Chemotherapy | |
Positive | Chemotherapy | |
Postmenopausal | ||
Negative† | Chemotherapy | |
Positive | Chemotherapy | |
* For all protocols involving chemotherapy, enrollment in a clinical trial is often considered. | ||
† Treatment of node-negative tumors also depends on tumor size and grade. | ||
ER = estrogen receptor; HER2 = human epidermal growth factor receptor 2; PR = progesterone receptor. | ||
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