Sedlis Criteria for External Pelvic Radiation After Radical Hysterectomy*
Lymphovascular Space Invasion | Stromal Invasion | Tumor Size (cm)† |
|---|---|---|
+ | Deep third | Any |
+ | Middle third | ≥ 2 |
+ | Superficial third | ≥ 5 |
− | Middle or deep third | ≥ 4 |
* Criteria apply to node-negative, margin-negative, parametria-negative cases. | ||
† Size is determined by clinical palpation. | ||
Based on Sedlis A, Bundy BN, Rotman MZ, et al: A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: A gynecologic oncology group study. Gynecol Oncol 73, 177–183, 1999. doi:10.1006/gyno.1999.5387 | ||
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