Some Oral Medications for Dyspepsia

Medication*

Comments

Proton pump inhibitors

With long-term use, elevated gastrin levels, but no evidence that this finding causes dysplasia or cancer

May cause abdominal pain or diarrhea

H2 blockers

Doses reduced in older adults

May cause constipation or diarrhea

Cytoprotective agent

Rarely constipation

May bind to other medications and interfere with absorption

Ranitidine (oral, IV, and over the counter) has been removed from the market in the United States and in many other countries because of unacceptable concentrations of N

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