Overview of Conjunctival and Scleral Disorders

ByZeba A. Syed, MD, Wills Eye Hospital
Reviewed/Revised Apr 2025
VIEW PROFESSIONAL VERSION

The conjunctiva is the membrane that lines the eyelid and loops back to cover the sclera (the tough white fiber layer covering the eye), right up to the edge of the cornea (the clear layer in front of the iris and pupil—see Structure and Function of the Eyes). The conjunctiva helps protect the eye by keeping small foreign objects and infection-causing microorganisms out and by contributing to the maintenance of the tear film.

The sclera is the tough, white, outer layer of the eyeball. The sclera provides the eyeball with structural strength and protects against penetration and rupture.

The episclera is a thin tissue layer overlying the sclera. The episclera contains tiny blood vessels that supply nutrients to the sclera.

An Inside Look at the Eye

The most common disorder of the conjunctiva is inflammation (conjunctivitis). Rarely, the sclera becomes inflamed (scleritis). Sometimes the episclera becomes inflamed (episcleritis).

There are many causes of inflammation, including

An injury may cause blood to accumulate beneath the conjunctiva (see Subconjunctival Hemorrhage).

Conjunctivitis tends to be relatively short-lived, but some kinds last for months or years. Long-standing conjunctivitis is often caused by chronic allergies, chronic infections (see Trachoma), and chronic irritation of the eye that occurs when an eyelid is turned outward (ectropion) or inward (entropion), by some eye drops, or by chronic dryness. Whatever the cause, people with conjunctivitis typically have similar symptoms, such as redness and discharge. Some types of conjunctivitis also cause itching or irritation.

quizzes_lightbulb_red
Test your KnowledgeTake a Quiz!
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID