Silent Lymphocytic Thyroiditis

(Postpartum Thyroiditis)

ByLaura Boucai, MD, Weill Cornell Medical College
Reviewed/Revised Feb 2024
VIEW PROFESSIONAL VERSION

Silent lymphocytic thyroiditis is painless, autoimmune inflammation of the thyroid that typically develops after childbirth and usually goes away on its own.

(See also Overview of the Thyroid Gland.)

Silent lymphocytic thyroiditis occurs most often among women, typically 3 to 4 months after childbirth, and causes the thyroid to become enlarged without becoming tender. The disorder tends to recur with subsequent pregnancies.

For several weeks to several months, people have an overactive thyroid gland (hyperthyroidism) followed by an underactive thyroid gland (hypothyroidism) before eventually recovering normal thyroid function.

Symptoms of Silent Lymphocytic Thyroiditis

Silent lymphocytic thyroiditis begins in the 3 to 4 months following childbirth. It starts with a hyperthyroid phase when the thyroid gland gets bigger without any pain or tenderness. Then, hypothyroidism develops before the condition usually resolves on its own.

First, symptoms of hyperthyroidism, such as increased heart rate and blood pressure, excessive sweating and feeling too warm, hand tremors (shakiness), and nervousness and anxiety, occur.

During the second phase, symptoms of hypothyroidism, which may include fatigue, weight gain, constipation, dry skin and hair, and cold intolerance, may occur.

Did You Know...

  • The word "silent" in silent lymphocytic thyroiditis indicates that the thyroid inflammation causes no pain or tenderness.

  • "Lymphocytic" refers to the type of white blood cells seen when thyroid tissue is examined with a microscope.

Diagnosis of Silent Lymphocytic Thyroiditis

  • Thyroid function blood tests

The diagnosis of silent lymphocytic thyroiditis is made based on a person's symptoms and the results of the examination and thyroid function blood tests. Rarely, doctors do a biopsy of the thyroid to confirm the diagnosis.

If a woman developed silent lymphocytic thyroiditis after a pregnancy, doctors usually test for the disorder after subsequent pregnancies.

Treatment of Silent Lymphocytic Thyroiditis

  • Beta-blocker for hyperthyroidism

  • Thyroid hormone replacement for hypothyroidism

During the period of hypothyroidism, the person may need to take thyroid hormone, usually for no longer than about 12 months. However, hypothyroidism becomes permanent in about 10% of people with silent lymphocytic thyroiditis, and these people must take thyroid hormone for the rest of their life.

Drugs Mentioned In This Article

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