How Medications Cross the Placenta
Some of the fetus's blood vessels are contained in tiny hairlike projections (villi) of the placenta that extend into the wall of the uterus. The mother's blood passes through the space surrounding the villi (intervillous space). Only a thin membrane (placental membrane) separates the mother's blood in the intervillous space from the fetus's blood in the villi. Medications in the mother's blood can cross this membrane into blood vessels in the villi and pass through the umbilical cord to the fetus.
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