Major Myeloproliferative Neoplasms
Disorder | Bone Marrow Characteristics | Blood Characteristics |
|---|---|---|
Increased number of mature and immature white cells | Increased number of a certain type of white blood cell (granulocytes) Sometimes increased number of platelets | |
Increased number of cells that produce the circulating blood cells | Increased number of red blood cells Usually, increased number of platelets, white blood cells, or both | |
Excess fibrous tissue replacing blood-producing cells | Decreased number of red blood cells (anemia) and an increased number of white blood cells Misshapen red blood cells The numbers of white blood cells and platelets often eventually decrease, but in some people they increase | |
Increased number of cells that produce platelets (megakaryocytes) | Increased number of platelets |