Medications for Serious Fungal Infections

Amphotericin B

Most fungal infections

Chills, fever, headache, vomiting, a low potassium level* in the blood, kidney failure, and anemia

Anidulafungin

Caspofungin

Micafungin

Aspergillus and candidal infections

Nausea, diarrhea, headache, liver inflammation, inflammation of the veins, and rash

Fluconazole

Candidal and other fungal infections, including coccidioidomycosis and cryptococcal infections

Nausea, rash, and liver inflammation

Flucytosine†

Candidal and cryptococcal infections

Nausea, vomiting, and bone marrow damage

Isavuconazole (also called isavuconazonium)

Aspergillosis and mucormycosis

Nausea, vomiting, and liver inflammation

Itraconazole

Fungal skin infections, histoplasmosis, blastomycosis, coccidioidomycosis, sporotrichosis, and aspergillosis

Nausea, diarrhea, liver inflammation, rash, headache, dizziness, a low potassium level* in the blood, high blood pressure, accumulation of fluid (edema), and heart failure

Posaconazole

Aspergillosis and mucormycosis

Nausea, vomiting, rash, and liver inflammation

Rezafungin

Candidal infections

Sensitivity to sunlight, abnormal liver test results, infusion-related reactions (flushing, sensation of warmth, hives, nausea, chest tightness)

Voriconazole

Aspergillosis and candidal infections, fusariosis, and scedosporiosis

Temporary disturbances in vision (such as blurred vision, changes in color vision, and sensitivity to light), nausea, vomiting, rash, and liver inflammation