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Some Antiviral Medications for Herpesvirus Infections

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Medication	Common Uses	Some Side Effects
Acyclovir Acyclovir	Genital herpes Herpes zoster (shingles) Chickenpox	Few serious side effects Rarely, kidney damage Rarely, in people with a weakened immune system, thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS)
CidofovirCidofovir	Cytomegalovirus infections, including retinitis (infection of the retina of the eye)	Kidney damage
Famciclovir Famciclovir	Oral and genital herpes Herpes zoster (shingles) Chickenpox	Few serious side effects
Foscarnet Foscarnet	Cytomegalovirus infections	Kidney damage Electrolyte disturbances Genital ulcers (reversible once the medication is stopped)
GanciclovirGanciclovir	Cytomegalovirus infections, including retinitis	Low white blood cell count
LetermovirLetermovir	Cytomegalovirus infections in people who have had a bone marrow and renal transplant	Nausea, vomiting, and diarrhea Swelling of lower legs or hands Cough Headache Fatigue Abdominal pain
MaribavirMaribavir	Cytomegalovirus infections that are resistant to other medications	Change in taste (dysgeusia) Nausea, vomiting, and diarrhea
Penciclovir (cream) Penciclovir (cream)	Cold sores	Few side effects Redness at site of application
Trifluridine (eye drops) Trifluridine (eye drops)	Herpes simplex keratitis (infection of the cornea)	Stinging of the eyes Swelling of the eyelids
Valacyclovir Valacyclovir	Genital herpes Herpes zoster (shingles) Chickenpox	Few serious side effects (similar to acyclovir) Few serious side effects (similar to acyclovir)
Valganciclovir Valganciclovir	Cytomegalovirus infections	Similar to ganciclovir (that is, a low white blood cell count)Similar to ganciclovir (that is, a low white blood cell count)
Vidarabine (as ointment applied to the eyes)	Herpes simplex keratitis	Irritation of the eyes Sensitivity to light