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Some Drugs That Interfere With Sleep

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Type	Examples
When the drug is used
Antiseizure medications	PhenytoinPhenytoin
Chemotherapy agents	All
Drugs that stimulate the brain	Amphetamines CaffeineCaffeine
Beta blockers	PropranololPropranolol
Steroids	Anabolic steroids Corticosteroids
Thyroid hormone preparations	—
When the drug is stopped
Recreational and illicit drugs	Cocaine Heroin Marijuana Phencyclidine
Drugs that slow the brain	Barbiturates Opioids Sedatives
When the drug is used or stopped
Alcohol	—
Antidepressants	Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetinereuptake inhibitors (SSRIs), such as fluoxetine Serotonin-norepinephrine reuptake inhibitors, such as duloxetinereuptake inhibitors, such as duloxetine Monoamine oxidase inhibitors (MAOIs), such as selegilineMonoamine oxidase inhibitors (MAOIs), such as selegiline Tricyclic antidepressants, such as amitriptylineTricyclic antidepressants, such as amitriptyline