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Definition of Diverticular Disease

ByJoel A. Baum, MD, Icahn School of Medicine at Mount Sinai;
Rafael Antonio Ching Companioni, MD, HCA Florida Gulf Coast Hospital
Reviewed/Revised Jul 2024
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Diverticula are saclike mucosal pouches that protrude from a tubular structure.

True diverticula of the gastrointestinal (GI) tract contain all layers of the GI wall. Esophageal diverticula (including Zenker diverticula) and Meckel diverticula are true diverticula.

False or pseudo-diverticula are mucosal and submucosal protrusions through the muscular wall of the bowel. Colonic diverticula are pseudodiverticula.

A single pouch is called a diverticulum and ≥ 2 pouches are called diverticula. These terms are occasionally used incorrectly.

Diverticulosis is the presence of 1 or more diverticula.

Diverticular disease is characterized as symptomatic diverticulosis (1).

Diverticulitis is inflammation with or without infection of a diverticulum.

General reference

  1. 1. Schultz JK, Azhar N, Binda GA, et al. European Society of Coloproctology: Guidelines for the management of diverticular disease of the colon. Colorectal Dis 22 (supplement 2):S5–S28, 2020. doi: 10.1111/codi.15140

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