Lefamulin

ByBrian J. Werth, PharmD, University of Washington School of Pharmacy
Reviewed/Revised May 2024
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Pharmacokinetics of Lefamulin

Indications for Lefamulin

  • Streptococcus pneumoniae

  • Staphylococcus aureus

  • Haemophilus influenzae

  • Legionella pneumophila

  • Mycoplasma pneumoniae

  • Chlamydophila pneumoniae

Contraindications to Lefamulin

Use of Lefamulin in Pregnancy and Breastfeeding

lefamulin should be considered in pregnant women until better safety data are available. Females with reproductive potential should use contraception while on therapy and for 2 days after the last dose.

Animal lactation studies suggest that lefamulin concentrates in breast milk. It is advised that lactating women taking lefamulin pump and discard while taking lefamulin and for 2 days after the last dose.

Adverse Effects of Lefamulin

Drugs Mentioned In This Article
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