Rumack-Matthew nomogram for single acute acetaminophen ingestions
Semilogarithmic plot of plasma acetaminophen levels vs time. Cautions for use of this nomogram:
The time coordinates refer to time after ingestion.
Serum levels drawn before 4 hours may not represent peak levels.
The graph should be used only in relation to a single acute ingestion.
The lower solid line 25% below the standard nomogram is included to allow for possible errors in acetaminophen plasma assays and estimated time from ingestion of an overdose.
Adapted from Rumack BH, Matthew H: Acetaminophen poisoning and toxicity. Pediatrics 55(6): 871–876, 1975; reproduced by permission of Pediatrics.
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