AJCC/TNM* Staging of Prostate Cancer*
Stage | Tumor | Regional Lymph Nodes | Distant Metastasis | Prostate-Specific Antigen Level† | Gleason Grade Group‡ |
|---|---|---|---|---|---|
I | cT1, cT2a, or pT2 | N0 | M0 | < 10 | 1 |
IIA | cT1, cT2a or pT2 | N0 | M0 | ≥ 10 but <20 | 1 |
cT2b or cT2c | N0 | M0 | < 20 | 1 | |
IIB | T1, T2 | N0 | M0 | < 20 | 2 |
IIC | T1, T2 | N0 | M0 | < 20 | 3 or 4 |
IIIA | T1, T2 | N0 | M0 | ≥ 20 | 1-4 |
IIIB | T3, T4 | N0 | M0 | Any PSA | 1-4 |
IIIC | Any T | N0 | M0 | Any PSA | 5 |
IVA | Any T | N1 | M0 | Any PSA | Any grade |
IVB | Any T | Any N | M1 | Any PSA | Any grade |
* For AJCC/TNM definitions, see table TNM Definitions for Prostate Cancer. Data adapted from American Cancer Society, Prostate Cancer AJCC/TNM Staging System. Accessed September 10, 2023. | |||||
† All PSA levels in this table represent both ng/mL and mcg/L (ie, 10 ng/mL = 10 mcg/L). | |||||
AJCC = American Joint Commission on Cancer; cT = clinical estimate of extent of disease (determined by physical exam, prostate biopsy, and imaging tests); PSA= prostate-specific antigen; pT = extent of disease that is based on pathologic examination of the prostate; TNM = tumor, node, metastasis. | |||||