Causes of Acute Kidney Injury Based on Laboratory Findings

Blood Test

Finding

Possible Diagnosis

Antiglomerular basement membrane (anti-GBM) antibodies

Positive

Anti-GBM disease (Goodpasture syndrome)

Antineutrophil cytoplasmic antibodies

Positive

Small-vessel vasculitis (eg, granulomatosis with polyangiitis or microscopic polyangiitis)

Antinuclear antibodies or antibodies to double-stranded DNA

Positive

Systemic lupus erythematosus (SLE)

Positive

Poststreptococcal glomerulonephritis

Creatine kinase or myoglobin level

Markedly elevated

Rhabdomyolysis

Complement titers

Low

Cholesterol embolization

Postinfectious glomerulonephritis

SLE

Subacute bacterial endocarditis

Protein electrophoresis (serum)

Monoclonal spike

Multiple myeloma

Uric acid level

Elevated

Cancer or tumor lysis syndrome (leading to uric acid crystals)

Prerenal acute kidney injury