Common IV Antibiotic Dosages for Acute Bacterial Meningitis*
Antibiotic | Dosage | |
|---|---|---|
Children > 1 month | Adults | |
CeftriaxoneCeftriaxone | 50 mg/kg every 12 hours | 2 g every 12 hours |
CefotaximeCefotaxime | 50 mg/kg every 6 hours | 2 g every 4–6 hours |
CeftazidimeCeftazidime | 50 mg/kg every 8 hours | 2 g every 8 hours |
CefepimeCefepime | 2 g every 12 hours | 2 g every 8–12 hours |
AmpicillinAmpicillin | 75 mg/kg every 6 hours | 2–3 g every 4 hours |
Penicillin GPenicillin G | 4 million units every 4 hours | 4 million units every 4 hours |
Nafcillin and oxacillinNafcillin and oxacillin | 50 mg/kg every 6 hours | 2 g every 4 hours |
Vancomycin†Vancomycin† | 15 mg/kg every 6 hours | 10–15 mg/kg every 8 hours |
MeropenemMeropenem | 40 mg/kg every 8 hours | 2 g every 8 hours |
Gentamicin and tobramycin†Gentamicin and tobramycin† | 2.5 mg/kg every 8 hours | 2 mg/kg every 8 hours |
Amikacin†Amikacin† | 10 mg/kg every 8 hours | 7.5 mg/kg every 12 hours |
RifampinRifampin | 6.7 mg/kg every 8 hours | 600 mg every 24 hours |
* For neonatal dosages, see table Recommended Dosages of Selected Parenteral Antibiotics for Neonates. | ||
† Renal function should be monitored. | ||