Depot Antipsychotic Drugs

Drug*

Dosage

Peak Level†

300–400 mg every month

5–7 days

12.5–50 mg every 2–4 weeks

1 day

12.5–50 mg every 1–2 weeks

2 days

25–150 mg every 28 days (3- to 5-week range is acceptable)

7 days

210–300 mg every 2 weeks or 300–405 mg every 4 weeks

7 days

234 mg on day 1; 156 mg on day 8; then 117 mg once monthly (dose range 39–234 mg monthly) starting 5 weeks later

13 days

12.5–50 mg every 2 weeks

35 days

* Drugs are given IM with Z-track technique.

† Time until peak level after a single dose is listed.

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