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Distinguishing Inflammatory versus Noninflammatory Joint Disease by Features

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Feature	Inflammatory	Noninflammatory
Systemic symptoms	Prominent, including fatigue	Unusual
Onset	Insidious in rheumatoid arthritis Sudden in gout or infection	Gradual
Morning stiffness	> 1 hour	< 30 minutes
Worst time of day	Morning	As day progresses
Effect of activity on symptoms (joint pain and stiffness)	Lessen with activity Worsen after periods of rest May also have pain with use	Worsen with activity Lessen with rest