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Hemodynamic Profiles of Pulmonary Hypertension

Type

Mean Pulmonary Artery Pressure at Rest

Pulmonary Artery Wedge Pressure*

Pulmonary Vascular Resistance†

Pre-capillary pulmonary hypertension (eg, chronic lung disorders, venous thromboembolic disease)

> 20 mm Hg

Normal ( 15 mm Hg)

Elevated (> 2 Wood units)

Post-capillary pulmonary hypertension (eg, left heart disease)

> 20 mm Hg

Elevated (> 15 mm Hg)

Normal (< 2 Wood units)

Combined pre-capillary and post-capillary pulmonary hypertension (eg, chronic pre-capillary vascular remodeling that occurs in patients who also have post-capillary pulmonary hypertension due to heart disease)

> 20 mmHg

Elevated (> 15 mm Hg)

Elevated (> 2 Wood units)

* Also called pulmonary artery occlusion pressure.

† Measured by right heart catheterization. Wood unit, also called hybrid resistance unit, is mm Hg × min/L.

Data from Humbert M, Kovacs G, Hoeper MM, et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2023;61(1):2200879. Published 2023 Jan 6. doi:10.1183/13993003.00879-2022

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