Location of Thrills and Associated Disorder

Over the base of the heart at the second intercostal space, just to the right of the sternum, during systole

Aortic stenosis

At the apex during systole

Mitral regurgitation

To the left of the sternum at the second intercostal space

Pulmonic stenosis

To the left of the sternum at the fourth intercostal space

Small muscular ventricular septal defect (Roger disease)