Nonopioid Analgesics

Indoles

50–100 mg, followed by 50 mg every 8 hours

75 mg every 12 hours IV or IM

200–400 mg every 6–8 hours

25–50 mg every 6–8 hours

150–200 mg every 12 hours

200–400 mg every 6–8 hours

Naphthylalkanone

1000–2000 mg every 24 hours

Oxicam

20–40 mg every 24 hours

Para-aminophenol derivative

650–1000 mg every 6–8 hours

Propionic acids

200–600 mg every 6 hours

50–200 mg every 12 hours

400 mg every 4 hours to 800 mg every 8 hours (maximum: 3200 mg/day†)

25–50 mg every 6–8 hours

250–500 mg every 12 hours

275–550 mg every 12 hours

600–1200 mg every 24 hours

Salicylates

650–1000 mg every 4–6 hours

Choline magnesium trisalicylate

870 mg every 12 hours

250–500 mg every 8–12 hours

750–2000 mg every 12 hours

Fenamates

Meclofenamate

50–100 mg every 6–8 hours

250 mg every 6 hours

Pyrazole

Phenylbutazone

100 mg every 6–8 hours up to 7 days

Pyrrolo-pyrrolo derivative

15–30 mg IV or IM every 6 hours or 20 mg orally, followed by 10 mg orally every 4–6 hours for maximum 5 days (assess creatinine every 4–6 doses, particularly in patients who are older or at risk of renal failure [eg, postoperative patients])

Selective COX-2 inhibitor

100–200 mg every 12 hours