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Oral Calcium Channel Blockers (CCBs) for Hypertension in Children

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Medication*	Some Adverse Effects	Comments
AmlodipineAmlodipine	Common adverse effects: Flushing, dizziness, peripheral edema Severe adverse effects: Angioedema	Contraindications include hypersensitivity to CCBs.
IsradipineIsradipine
Nifedipine, extended-release†Nifedipine, extended-release†
* All of these medications are dihydropyridines, which have mainly vascular effects and minimal cardiac effects.
† Nifedipine immediate-release tablet is not longer recommended because of the potential for rapid blood pressure drop.† Nifedipine immediate-release tablet is not longer recommended because of the potential for rapid blood pressure drop.