Potentially Hepatotoxic Drugs

Finding

Drug

Hepatocellular: Elevated ALT

Antiretroviral therapy drugs

Germander

Kava

NSAIDs

PD-1/PD-L1 inhibitors

Statins

Tetracyclines

Trovafloxacin

Valproate

Cholestatic: Elevated alkaline phosphatase and total bilirubin

Anabolic steroids

Oral contraceptives

Erythromycins

Estrogens

Phenothiazines

Tricyclic antidepressants

Mixed: Elevated alkaline phosphatase and ALT

Sulfonamides

ALT = alanine aminotransferase; AST= aspartate aminotransferase; NSAID = nonsteroidal anti-inflammatory drug.