Representative Type 1, Type 2, and Mixed-Effect Chemicals With Acute Local Effects on the Respiratory Tract

Type

Example

Name and (North Atlantic Treaty Organization [NATO] code)

Type 1 (affects large airways)

Acetaldehyde

Acrolein

Ammonia

Formaldehyde

Hydrogen chloride

Hydrogen fluoride

Ozone

Riot-control agents (eg, chlorobenzylidenemalononitrile [CS], chloroacetophenone [CN], oleoresin capsicum [OC])

Smoke particles from ordinary combustion or from certain military smokes (eg, titanium tetrachloride, fog oil)

Sulfur dioxide

Sulfur mustard (H, HD)

Type 2 (affects terminal and respiratory bronchioles, alveolar sacs, and alveoli)

Carbon tetrachloride

Chloropicrin (PS, also sometimes considered a riot-control agent)

Diphosgene (DP)

Methyl isocyanate

Oxides of nitrogen

Perfluoroisobutylene (PFIB)

Phosgene (CG)

Phosgene oxime (CX)

Mixed effect (both type 1 and type 2)

Chloramines

Chlorine (CL)

Lewisite (L)