Some Bartonella Infections

Species

Manifestations*

At Risk

Insect Vector

Treatment

Bacillary angiomatosis

B. henselae, B. quintana

Multiple papules and subcutaneous nodules (purple to bright red skin lesions)

Disseminated visceral disease

Lymphadenopathy

Hepatosplenomegaly

Immunocompromised patients

Lice, fleas

Trench fever

B. quintana

Prolonged or recurrent fever

Bacteremia

Endocarditis

People living in conditions of crowding or poor hygiene

Immunocompromised patients

Body louse

Cat-scratch disease

B. henselae

Regional lymphadenopathy, painless papules

Fever

Endocarditis (often in patients who have had a predisposing valvular heart disorder)

Encephalopathy

Neuroretinitis

Owners of cats

Immunocompromised patients

Possibly cat fleas (which also transmit the organism among cats)

Oroya fever, verruga peruana (Carrión disease)

B. bacilliformis

Oroya fever: Acute febrile hemolytic anemia

Verruga peruana: Skin lesions similar to those in bacillary angiomatosis

Salmonella bacteremia

Secondary infections

Residents of the Andes Mountains at elevations of 600–2400 m

Phlebotomus sandflies

* In normal host.

† Treatment of uncomplicated cat-scratch disease is not usually required in patients with a normal immune system, but it is often given to possibly decrease the duration of symptoms (1).