Some Clinical Uses of Macrolides

Macrolide

Indication

Comments

Infection due to Mycoplasma pneumoniae, Legionella species, or Bordetella pertussis

Eradication of Corynebacterium diphtheriae in carriers

Antibiotics of choice

Symptomatic cat-scratch disease (Bartonella henselae)

Bacillary angiomatosis and peliosis hepatis in patients with AIDS (involving B. henselae or B. quintana)

Cerebral toxoplasmosis

Used with other antibiotics

Babesiosis

Used with other antibiotics

Chlamydia trachomatis urethritis and cervicitis

Mycobacterium avium complex and other nontuberculous mycobacteria

Part of a multidrug regimen

Uncomplicated skin infections

Acne

Topical use

Bowel preparation before gastrointestinal tract surgery

Taken orally and used with an oral aminoglycoside

Clostridioides difficile (formerly Clostridium difficile)

Antibiotic of choice for initial episode

In these topics