Some Drugs and Toxins That Can Cause Jaundice
Mechanism | Drugs or Toxins |
|---|---|
Increased bilirubin production | Drugs that cause hemolysis (common among patients with glucose-6-phosphate dehydrogenase [G6PD] deficiency |
Decreased hepatic uptake | |
Decreased conjugation | |
Hepatocellular dysfunction | nonsteroidal anti-inflammatory drugs, statins, many others, many drug combinations Amanita phalloides mushrooms, carbon tetrachloride, phosphorus (see Hydrocarbon Poisoning and Volatile Solvents) |
Intrahepatic cholestasis | anabolic steroidsherbal preparations), oral contraceptives, phenothiazines |
In these topics