Some Types of Physiologic and Drug-Receptor Proteins

Type

Structure

Cellular Location

Examples

Multisubunit ion channels

Some Types of Physiologic and Drug-Receptor Proteins

Cell surface transmembrane

Acetylcholine (nicotinic)

GABA A

Glutamate

G-protein–coupled receptors

Some Types of Physiologic and Drug-Receptor Proteins

Cell surface transmembrane

Acetylcholine (muscarinic)

Alpha- and beta-adrenergic receptor proteins

Eicosanoids

Protein kinases

Some Types of Physiologic and Drug-Receptor Proteins

Cell surface transmembrane

Growth factors

Insulin

Peptide hormones

Transcription factors

Some Types of Physiologic and Drug-Receptor Proteins

Cytoplasm

Steroid hormones

Thyroid hormone

GABA = gamma-aminobutyric acid; GDP = guanosine diphosphate; GTP = guanosine triphosphate.