Manganese Deficiency

Manganese (Mn), necessary for healthy bone structure, is a component of several enzyme systems, including manganese-specific glycosyltransferases and phosphoenolpyruvate carboxykinase. Median intake is between 1.6 and 2.3 mg/day; absorption is 5 to 10%.

Manganese deficiency has not been conclusively documented, although one experimental case in a volunteer resulted in transient dermatitis, hypocholesterolemia, and increased alkaline phosphatase levels.

(See also Overview of Mineral Deficiency and Toxicity.)